There have been plenty of computer games based on comics properties over the years but not too many that have emulated the comics medium itself. 1988's Batman: The Caped Crusader is one notable exception:
Sega's Comix Zone for the Mega Drive is a more sophisticated version of what Batman was getting at:
Perhaps we were waiting for the right technology to come along; 2013 will see the release of Framed from Loveshack Entertainment. What's most interesting to me about Framed is that unlike the earlier games, the medium of comics isn't only a stylistic element but is fundamental to the core game mechanics:
From the look of it, Framed seems to be a sort of action-puzzle hybrid in a similar vein to the original Lemmings titles, but the parameters of the game are not yet clear; there's no time limit shown in the concept video, nor is there any indication of whether the player can only work with what's there at the start or if they can bring in new panels. It may turn out that Framed is going to be a stylish but casual amusement rather than a true brain-busting puzzler but even if that turns out to be the case, as a fan of comics and computer games I applaud the concept and I'm keen to see more as the game develops.